Articles & Papers – 4

2003

A case of malignant atrophic papulosis successfully treated with nicotine patches

Link: http://www.degosdisease.org/info/nicotine_patches_paper

Authors: T.Kanekura, Y.Uchino, T.Kanzaki

Department of Dermatology, Kagoshima University Faculty of Medicine, 8-35-1 Sakuragaoka, Kagoshima 890–8520, Japan

Reference: Letter to British Journal of Dermatology, 2003

2002

Malignant atrophic papulosis in an infant

Link: http://www.docguide.com/news/content.nsf/PaperFrameSet?OpenForm&refid=2…

Authors: A. Torrelo, J. Sevilla, I.G. Mediero, D. Candelas and A. Zambrano

Reference: British Journal of Dermatology, Vol. 146, Iss. 5, p. 916, May 2002

Papulosis maligna atrophicans Degos – Nicht immer maligne!

Link: http://link.springer-ny.com/link/service/journals/00105/bibs/2053001/20530042….

Authors: C. Mensing, H. Mensing

Reference: Der Hautarzt, Vol. 53 No. 1, pp. 42-46, Jan 2002

Benign Degos’ disease developing during pregnancy and followed for 10 years

Link: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&…

Authors: Bogenrieder T, Kuske M, Landthaler M, Stolz W

Department of Dermatology, University of Regensburg, Germany

Reference: Acta Derm Venereol. 2002;82(4):284-7.

Correspondence: Bogenrieder T <bogenrieder@wistar.upenn.edu>

2001

Papulosis maligna atrophicans (Köhlmeier-Degos) Diagnose, Therapie, Verlauf

Link: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&…

Authors: Vicktor C, Schultz-Ehrenburg U

Reference: Der Hautarzt, Vol. 52 No.8, pp. 734-7, Aug 2001

The treatment of a Degos patient, using aspirin, Interferon and pentoxifylline.

Malignant atrophic papulosis (Degos’ disease): clinicopathological correlations

Link: http://www.blackwell-synergy.com/links/doi/10.1046/j.1468-3083.2001.00216.x/abs/

Authors: TA Chave, S Varma, GK Patel, AG Knight

Reference: Journal of the European Academy of Dermatology & Venereology, Volume 15 Page 43 – January 2001

Benign Cutaneous Degos Disease: a case report with emphasis on histopathology as papules chronologically evolve.

Link:

Authors: Harvell J D , Williford PL, White WL,

Reference: American Journal of Dermatopathology 23 (2) 116-23

2000

Posterior subcapsular cataract in Degos disease

Link: http://www.sciencedirect.com/science/article/pii/S0002939400004608

Authors: Robert Egan MDSimmons Lessell MD

Reference: American Journal of Ophthalmology June 2000, Vol.129(6):806–807, doi:10.1016/S0002-9394(00)00460-8

Abstract
PURPOSE: To report an association of posterior subcapsular cataract with Degos disease.

METHOD: Case report of a 42-year-old man.

RESULTS: A posterior subcapsular cataract developed in the patient’s left eye at age 43 years, 1 year before his death. The diagnosis of Degos disease was confirmed pathologically by skin biopsy and at necropsy.

CONCLUSION: Posterior subcapsular cataract may be associated with Degos disease in addition to previously reported findings, including visual field defects, third cranial nerve palsies, blepharoptosis, and optic atrophy.

Degos’ disease

Link:

Authors: Füsun Özder Güven MD, Kübra Eren Bozdağg MD, Murat Ermete MD andAhmet Karaman MD

Dermatology and Pathology Departments of Atatürk Training Hospital, Izmir, Turkey

Reference: International Journal of Dermatology Volume 39, Issue 5, pages 361–362, May 2000

A 47-year-old woman presented with slightly pruritic, burning lesions on her submammary area and legs of 3.5 years’ duration. Similar lesions had appeared on her arms and feet. She was hospitalized at the Pulmonary Diseases Hospital, İzmir, with a complaint of thoracic pain, and was diagnosed with nonspecific pleuritis by pulmonary X-ray, thoracic computed tomography (CT) scanning, bacterial cultures of phlegm, and pleural biopsy examination.

Degos’ disease with constrictive pericarditis: a case report

Link: http://www.biomedexperts.com/Abstract.bme/10875739/…

Authors: Yukiiri K, Mizushige K, Ueda T, Tomohiro A, Tanimoto K, Matsuoka Y, Kubota Y, Matsuo H

Reference: Japanese circulation journal 2000;64(6):464-7

1998

Malignant Atrophic Papulosis

Link: http://www.ijdvl.com/article.asp?issn=0378-6323;year=1998;volume=64;issue=2;…

Authors: Mittal RR, Bansal N, Gupta S

Reference: Indian J Dermatol Venereol Leprol 1998;64:93-94

1997

Köhlmeier-Degos’s disease with primary intestinal manifestation

Link: http://cat.inist.fr/?aModele=afficheN&cpsidt=2839676

Authors: Fruhwirth J, Mischinder H J, Werkgartner G, Beham A, Pfaffenthaller E C

Clinical Division of General Surgery, Dept. of Surgery, Dept. of Pathological Anatomy, and Dept. of Dermatology, Medical School of Karl-Franzens University, Graz, Austria

Reference: Scandinavian journal of gastroenterology (Scand. j. gastroenterol.), 1997, vol. 32, no10, pp. 1066-1070

PAPULOSIS ATROFIANTE MALIGNA O ENFERMEDAD DE DÉGOS

Link: http://www.actasdermo.org/es/reuniones-mensuales-1997/articulo/13003422/

Authors: Dres. Lázaro T, Hdez. Cano N, Vidaurrazaga C, Contreras F, Mayor M, Burón I, Casado M. Hospital La Paz.

Hospital La Paz, Madrid

Reference: Actas Dermosifiliogr., 1998;89,S1:72-75

181 «PAPULOSIS ATROFIANTE MALIGNA O ENFERMEDAD DE DÉGOS», por los Dres. Lázaro TE, Hernández-Cano N, Vidaurrazaga C, Contreras F, Burón I, Mayor M, Casado M. Servicio de Dermatología del Hospital La Paz. Madrid.

INTRODUCCIÓN

La papulosis atrofiante maligna es una enfermedad multisistémica, de etiología desconocida, que se caracteriza por una endarteritis con afectación de forma casi constante de la piel. Con frecuencia también se afectan el aparato gastrointestinal, neurológico y oftalmológico.

1996

Small bowel fistulae in Degos’ disease: a case report and literature review.

Link: http://www.ncbi.nlm.nih.gov/pubmed/8855750

Authors: Atchabahian A1, Laisné MJ, Riche F, Briard C, Nemeth J, Valleur P.

Reference: Am J Gastroenterol. 1996 Oct;91(10):2208-11.

Degos’ disease (malignant atrophic papulosis) is a rare, progressive, small- and medium-size arterial occluding disease, leading to tissue infarction and initially involving the skin. We report a case with bowel involvement followed by enterocutaneous fistulae. Diagnostic laparoscopy with jejunal biopsy was followed by jejunal perforations, peritonitis, and fistulae leading to death after a 4-month course in the intensive care unit. The usual treatment of enterocutaneous fistula by somatostatin and parenteral nutrition was ineffective in this case.

Skin lesion with a fatal neurologic outcome (Degos’ disease)

Link: http://www.neurology.org/content/46/3/636

Authors: P. Subbiah, MD, E. Wijdicks, MD, M. Muenter, MD, J. Carter, MD and S. Connolly, MD

Reference: doi: 10.1212/WNL.46.3.636 Neurology March 1996 vol. 46 no. 3 636-640

Degos’ disease, or malignant atrophic papulosis, is a rare multisystem vasculopathy of unknown etiology. Kohlmeier [1] first reported it in 1941 as a form of thromboangiitis obliterans but in 1942 Degos et al. [2] described it as a distinct entity. The clinical hallmark of the disease is a cutaneous eruption on the trunk and extremities that is characterized as umbilicated papules with atrophic “porcelain white’‘ centers that are painless but occasionally itchy.

1995

Absence of antiphospholipid and anti-endothelial cell antibodies in malignant atrophic papulosis: a study of 15 cases.

Link: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&…

Authors: Assier H, Chosidow O, Piette JC, Boffa MC, Youinou P, Thomas L, Caux F, Cribier B, Bonnet-Blanc JM, Guillet G, et al.

Department of Internal Medicine, Hopital de la Pitie-Salpetriere, Paris, France.

Reference: J Am Acad Dermatol. 1995 Nov;33(5 Pt 1):831-3.

1994

Report of a case of malignant atrophic papulosis or Degos disease

Link: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&…

Authors: De Leo G, Losacco T, Punzo C, Lavacca M, Pitzalis MV, De Tommaso C, Posca A

Istituto di Semeiotica Chirurgica, Universita degli Studi di Bari.

Reference: G Chir. 1994 Mar;15(3):97-102.

1993

Malignant atrophic papulosis. A report of two cases with altered fibrinolysis and platelet function

Link: http://cat.inist.fr:80/?aModele=afficheN&cpsidt=4879862

Authors: Vazquez-Doval FJ, Ruiz De Erenchun F, Paramo JA, Quintanilla E

Univ. Navarra, univ. clin. Navarra, dep. dermatology, 31080 Pamplona, Spain

Reference: Clinical and experimental dermatology, 1993, vol. 18, no5, pp. 441-444

1990

An atypical paediatric case of malignant atrophic papulosis (Köhlmeier-Degos disease)

Link: http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&…

Authors: Barabino A, Pesce F, Gatti R, Colotto P, Nobili F, Colacino R, Giampalmo A

III Paediatric Department G, Gaslini Scientific Institute, Genova, Italy

Reference: Eur J Pediatr. 1990 Apr;149(7):457-8

1987

The pathology and pathogenesis of malignant atrophic papulosis (Degos’ disease). A case study with reference to other vascular disorders.

Link: http://www.ncbi.nlm.nih.gov/pubmed/3588409

Authors: Molenaar WM, Rosman JB, Donker AJ, Houthoff HJ.

Reference: Pathol Res Pract. 1987 Feb;182(1):98-106.

Correspondence: <PMID: 3588409 [PubMed – indexed for MEDLINE]>

The morphology and immunohistology in a case of malignant atrophic papulosis (Degos’ disease), a rare vascular disorder of unknown etiology, are described. The vascular lesions affected middle class and small arteries and veins throughout the body and were histologically characterized by intimal proliferation in the absence of any appreciable inflammation. The lesions were categorized as early, intermediate or late. Early lesions consisted of cellular proliferation and edema of the intima with signs of immune complex deposition (IgM, C3).

1986

Familial malignant atrophic papulosis (Degos’ disease)–additional evidence for heredity and a benign course.

Link: http://www.ncbi.nlm.nih.gov/pubmed/3942684

Authors: Habbema L, Kisch LS, Starink TM.

Reference: http://www.ncbi.nlm.nih.gov/pubmed/3942684

Correspondence: <PMID: 3942684 [PubMed – indexed for MEDLINE]>

1984

Six cases of malignant atrophic papulosis (Degos’ disease) occurring in one family.

Link: .http://www.ncbi.nlm.nih.gov/pubmed/6487548

Authors: Kisch LS, Bruynzeel DP.

Reference: Br J Dermatol. 1984 Oct;111(4):469-71.

Correspondence: <PMID: 6487548 [PubMed – indexed for MEDLINE]>

A family is described in which a mother and five of her children were affected by malignant atrophic papulosis. This suggests that genetic factors might be involved in this condition.

Familial Degos’ atrophic papulosis (mother-daughter). Article in French

Link: http://www.ncbi.nlm.nih.gov/pubmed/6721361

Authors: Moulin G, Barrut D, Franc MP, Pierson A.

Reference: Ann Dermatol Venereol. 1984;111(2):149-55.

Correspondence: <PMID: 6721361 [PubMed – indexed for MEDLINE]>

Degos’ disease (malignant atrophic papulosis) occurring in mother and daughter is described. Mother’s eruption is composed of multiple characteristic lesions (up to 600). She does not have any gastrointestinal, neurological nor other visceral manifestations after a 9-year course. One year after the onset of the disease, she had a daughter. The pregnancy was normal and the newborn did not have any cutaneous manifestation. The daughter’s first skin lesion appeared when she was 3-months old.